APRI
The AST to platelet ratio index was derived in chronic hepatitis C and is used in WHO guidance where elastography is unavailable. It is less accurate in MASLD.
Enter the values above.
Interpretation
| APRI | Meaning |
|---|---|
| Below 0.5 | Significant fibrosis (F2 or more) unlikely |
| 0.5 to 1.0 | Indeterminate |
| Above 1.0 | Cirrhosis possible (sensitive cut-off) |
| Above 1.5 | Significant fibrosis likely |
| Above 2.0 | Cirrhosis likely (specific cut-off, used by WHO) |
Reference
Wai CT, Greenson JK, Fontana RJ, et al. A simple noninvasive index can predict both significant fibrosis and cirrhosis in patients with chronic hepatitis C. Hepatology. 2003;38(2):518-526.