GI ToolsGastroenterology and hepatology

Fibrotic NASH Index (FNI)

The Fibrotic NASH Index screens for fibrotic MASH (steatohepatitis with activity and fibrosis of stage 2 or more) in people with metabolic risk factors, using three routine tests.

Blood results

To convert from mmol/mol: divide by 10.93 and add 2.15.

Enter the values above.

Related resources: MASLD

How it is worked out

FNI = ex ÷ (1 + ex), where x = −10.33 + 2.54 × ln AST + 3.86 × ln HbA1c (%) − 1.66 × ln HDL (mg/dL). HDL in mmol/L is multiplied by 38.67.

Reference

Tavaglione F, Jamialahmadi O, De Vincentis A, et al. Development and validation of a score for fibrotic nonalcoholic steatohepatitis. Clin Gastroenterol Hepatol. 2023;21(6):1523-1532.e1.