Functional heartburn (Rome IV)

Functional heartburn is heartburn that does not respond to acid suppression, with normal acid exposure and no association between symptoms and reflux on pH-impedance monitoring. The Rome IV criteria are summarised here in our own words, and are a guide to a positive diagnosis alongside appropriate investigation. See the Rome Foundation for the original criteria.

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Reference

Aziz Q, Fass R, Gyawali CP, et al. Functional esophageal disorders. Gastroenterology. 2016;150(6):1368-1379.