GI ToolsGastroenterology and hepatology

Opioid-induced constipation (Rome IV)

Opioid-induced constipation has no minimum duration: it can start with the first dose. The Rome IV criteria are summarised here in our own words, and are a guide to a positive diagnosis alongside appropriate investigation. See the Rome Foundation for the original criteria.

New or worse constipation when starting, changing or increasing an opioid, with two or more of
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Reference

Mearin F, Lacy BE, Chang L, et al. Bowel disorders. Gastroenterology. 2016;150(6):1393-1407.